Purpose ; This Study was aimed to Investigate the different effects according to the form and term of moxibustion therapy on the depression of the immune response induced by cold stress in rats.
Methods ; The control group and the Sample groups were also exposed to cold stress and they were redivided into 14, 2, 3, 4 day-group by total term of time exposed to cold stress. The sample group were classified into sample I (direct moxibustion therapy), sample II (Bongrae-moxibustion therapy) according to the form of moxibustion, To all of sample groups, each moxibustion therapy were peformed 2 times a day on the loci corresponding Bi-su(BL20) of Human body and Blank loci.
Experimental studies were performed for the observation of the No. of RBC, WBC and Lymphocyte in blood CD4^+ T helper cell count, spleen CD4^+ T helper cell count, axillary lymph node CD4^+ T helper cell count, and Thymus CD4^+ T helper cell count in rats exposed to cold stress.
Results ; 1. The CD4^+ T cell count in blood was increased statistically significant in all of the sample I (1, 2, 3, 4-day group) as compared with the control group. And in the sample II only 2-day group gained the statistical significance as compared with the control group.
2. The CD4^+ T cell count in axillyary lymph node was increased statistically significant in all of the sample I (1, 2, 3, 4-day group) compared with the control group. But all of the sample II were increased without the statistical significance compared with the control group.
3. The CD4^+ T cell count in Spleen was increased with the statistical nonsignificance in all of the sample I (1, 2, 3, 4-day group) as compared with the control group. And in the sampleII only 1-day group gained the statistical significance as compared with the control group. all of the sample I (1, 2, 3, 4-day group) as compared with the control group. And in the sampleII only 1-day group gained the statistical significance as compared with the control group.
4. The CD4^+ T cell count in Thymus was increased with the statistical non significance in the Conclusions ; On the depression of the immune response induced by cold stress in rats, direct moxibustion therapy is more effective than Bongrae-moxibustion therapy for the recovery of immune response.
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